Creating Memory: Vaccines & Immunity

We talk with Dr. Cassie Simonich, Pediatric Infectious Diseases Fellow at the University of Washington, WA, who uses RSV pseudoviruses and deep mutational scanning approaches to define the evolution of the RSV fusion protein to escape natural or vaccine-induced immunity and monoclonal antibody treatments.

We talk with Dr. Alba Grifoni, Research Assistant Professor scholar in the Center for Vaccine Innovation at the La Jolla Institute for Immunology, CA, who uses bioinformatic analyses and immune focusing approaches to improve protective T cell responses induced by vaccines.

We talk with Dr. Alexander Cohen, Postdoctoral Scholar in the Division of Biology and Biological Engineering at the California Institute of Technology, CA, who uses immune focusing approaches to design vaccines that generate antibodies against conserved epitopes on viral antigens.

We talk with Dr. Hanover Matz, Postdoctoral Research Associate in Pathology and Immunology at Washington University School of Medicine, MO, who uses human vaccine studies as well as comparisons to other vertebrate immune systems to understand how adaptive immunity has evolved and how we can use that information to generate more effective vaccines.

We talk with Dr. Seth Zost, Research Instructor in the Vanderbilt Vaccine Center at Vanderbilt University Medical Center, TN, who is developing new approaches to define how antibody responses to SARS-CoV-2 and influenza viruses shape the antigenic evolution of these viruses.