Creating Memory: Vaccines & Immunity

We talk with Dr. JoAnne Flynn, Professor and Chair of the Department of Microbiology and Molecular Genetics at the University of Pittsburgh School of Medicine, who uses non-human primate models of Mycobacterium tuberculosis (Mtb) to determine who are the 'players' in the protective immune response for TB. 

We talk with Dr. James Crowe, Director of the Vanderbilt Center for Antibody Therapeutics and Professor of Pediatrics, Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, who seeks to discover, manufacture and stockpile highly potent monoclonal antibodies ahead of the next epidemic.

We talk with Dr. Antonio DiGiandomenico, Senior Director and Head of Microbial Antibodies and Technologies within AstraZeneca’s early Infectious Disease unit, who uses new delivery modalities to enhance monoclonal antibody therapeutics for bacterial pathogens such as Pseudomonas aeruginosa.

We talk with Dr. Christopher Hunter, Professor and Director of the Institute for Infectious & Zoonotic Diseases in the University of Pennsylvania School of Veterinary Medicine in Philadelphia, PA, who studies the initiation of immunity by parasites and mRNA vaccines to inform new vaccine development.

We talk with Dr. Gagandeep Kang, Director of Enterics, Diagnotics, Genomics & Epidemiology at the Gates Foundation in Seattle, WA, who leads efforts to understand mechanisms of action to develop new and better vaccines for rotavirus, cholera, typhoid and shigella.