Creating Memory: Vaccines & Immunity

Episode 9: Using mosaic nanoparticle vaccines to generate broadly protective immmune responses

We talk with Dr. Alexander Cohen, Postdoctoral Scholar in the Division of Biology and Biological Engineering at the California Institute of Technology, CA, who uses immune focusing approaches to design vaccines that generate antibodies against conserved epitopes on viral antigens.

Episode 8: Using comparative immunology to design better vaccines

We talk with Dr. Hanover Matz, Postdoctoral Research Associate in Pathology and Immunology at Washington University School of Medicine, MO, who uses human vaccine studies as well as comparisons to other vertebrate immune systems to understand how adaptive immunity has evolved and how we can use that information to generate more effective vaccines.

Episode 7: Novel approaches to dissect antibody responses to respiratory viruses

We talk with Dr. Seth Zost, Research Instructor in the Vanderbilt Vaccine Center at Vanderbilt University Medical Center, TN, who is developing new approaches to define how antibody responses to SARS-CoV-2 and influenza viruses shape the antigenic evolution of these viruses.

Episode 6: Using phylogenetic inference to design vaccine antigens

We talk with Dr. Brett Case, Instructor of Infectious Diseases at Washington University School of Medicine, MO, who studies how to generate cross-protective and sterilizing mucosal immunity following vaccination.

Episode 5: New therapeutic strategies for treating mycobacterium tuberculosis

We talk with Dr. Christina Stallings, Professor of Molecular Microbiology at Washington University School of Medicine, MO, who studies host molecules important for mycobacterium tuberculosis pathogenesis to develop new therapies to treat mycobacterium infection and disease. 

Episode 4: From AIDS to Zika

We talk with Dr. Robert Seder, Chief of the Cellular Immunology Section of the Vaccine Research Center in Bethesda, MD, who studies how changing the route of vaccination can improve immunity and protection against pathogens.

Episode 3: Immunobiology of pregnancy and birth

We talk with Dr. Nardhy Gomez-Lopez, a professor at Washington University School of Medicine in St. Louis, MO, who studies the immunology of pregnancy and birth to identify biomarkers that may predict adverse outcomes.

Episode 2: Evolution of antibodies in the germinal center

We talk with Dr. Gabriel Victora, an associate professor and HHMI investigator at The Rockefeller University in NY, NY, who studies how antibodies are generated in response to infection and immunization through the evolutionary process of affinity maturation in germinal centers.